Dr Marian Raschke
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Head of Mechanistic Toxicology
Bayer AG
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Research Interests
in vitro toxicology, 3D models, Liver models / hepatotoxicity, Intestinak models / GI toxicity, High Content Imaging, IVIV / PBPK modeling
Exchange with other users and vendors on achievements and challenges using commercially available organs-on-chip platforms and models especially for safety testing // We are currently applying Mimetas OrganoPlates and the TissUse platform in the lab // I am happy to share and discuss our experiences.
Collaboration Interests
Models for investigating intestinal, hepatotoxicity, and bone marrow suppression, vascularization // Exchange on general questions around regulatory requirements, controlling quality and robustness, topics around in vitro exposure (equivalent dosing, IVIVE, PBPK modeling, scaling) etc.