Dr Leonard Nelson

Senior Research Fellow

Research Interests

Hepatology, Liver tissue engineering, Drug-induced liver injury, Liver disease (NAFLD; NASH; Cancer), Synthetic biology, Alzheimer's disease

Our research is focused on developing human liver tissue (2D-3D) organotypic models, mechanisms underlying liver disease utilizing in vitro human disease models (DILI; fatty liver disease (MAFLD; NAFLD-NASH); and cholangiocarcinoma), study of the liver–brain axis in Alzheimer’s disease, as well as integrating synthetic biological engineering approaches to the above and for pharmaceutical applications. Integration of these into Organ-on-a-Chip technologies we think would provide synergy to develop a range of disruptive tools for commercial exploitation.

Collaboration Interests

We, therefore, seek technologists/bioengineers and collaborative links with industry (Pharma; Biotech) with novel Organ-on-a-Chip platforms, with innovative solutions - that are amenable to the above applications.