Dr Luis Marcos
PhD student
Loughborough Unicersity
Research Interests
Retinal Organoids, Retina on chip, Microfluidics, Stem cells, Organ on chip, Tissue Engineering
Microfluidic, or lab-on-a-chip, platforms address the complexity issues of conventional 3D models regarding cell numbers and functional connectivity. Regulation of biochemical/biomechanical conditions can create dynamic structures, providing microenvironments that permit tissue formation while quantifying biological processes at a single cell level.
Modern bio-fabrication techniques allow for retinal organoids, to date the most reliable in vitro system in terms of cells spatiotemporal development, maturation and functionality, to be combined with microfluidic devices to create anato-physiologically accurate structures or “retina-on-a-chip” devices that could revolution ocular sciences.