Dr Daniel Scotcher

United Kingdom

Research Interests

Kidney, Drug transport, Drug-drug interaction, PBPK modelling, Pharmacokinetics, Renal impairment

My research focus is mechanistic modelling for (i)projection of clinical pharmacokinetic endpoints from in vitro and systems data, and (ii) simulating effect of disease on pharmacokinetics of drugs (e.g., renal impairment). Most research focussed on drug transporters in kidney and liver. We are exploring the utility of Organ-on-a-chip systems to inform our PBPK models and improve quantitative translation. https://www.research.manchester.ac.uk/portal/daniel.scotcher.html