Prof Alistair Elfick

Head of Institute for Bioengineering; Depute Director, UK Centre for Mammalian Synthetic Biology

Research Interests

Synthetic Biology, Tissue engineering, Materials science, Liver disease models, Alzheimer disease models

Our research is focused on developing human liver tissue (2D-3D) organotypic models, mechanisms underlying liver disease utilizing in vitro human disease models (DILI; fatty liver disease; and cholangiocarcinoma), study of the liver–brain axis in Alzheimer’s disease, as well as integrating synthetic biological engineering approaches to the above and for pharmaceutical applications. Integration of these into Organ-on-a-Chip technologies we think would provide synergy to develop a range of disruptive tools for commercial exploitation. We, therefore, seek technologists/bioengineers with novel Organ-on-a-Chip platforms, with innovative solutions - that are amenable to the above applications.